Mono Propylene Glycol USP/IND
Mono Propylene Glycol USP/IND
Product Details
Areas of Use
Applications of Monopropylene Glycol (MPG)
Monopropylene Glycol (MPG) is a versatile chemical widely used across multiple industries due to its properties as a solvent, humectant, and antifreeze agent. Below is an overview of its key applications:
1. Food and Beverage Industry
- Food Additive: MPG is approved for use as a food additive and functions as a humectant, solvent, and preservative. It helps retain moisture in products such as baked goods, confectionery, and beverages.
- Flavor and Color Carrier: It acts as a carrier for flavors, extracts, and food colorings, ensuring uniform distribution and product stability, particularly in soft drinks and confectionery.
2. Pharmaceutical and Medical Industry
- Solvent in Medicines: MPG is commonly used to dissolve active pharmaceutical ingredients in syrups, oral solutions, and injectable formulations, ensuring effective drug delivery.
- Humectant in Topical Products: It is included in creams, ointments, and lotions to retain moisture and enhance product texture and performance.
- Low Toxicity: Due to its relatively low toxicity, MPG is suitable for both ingestible and topical medical applications.
3. Cosmetics and Personal Care Industry
- Moisturizer and Humectant: MPG is widely used in personal care products such as lotions, shampoos, and deodorants to maintain moisture and formulation stability.
- Fragrance Solvent: It acts as a solvent for perfumes and fragrances, enabling consistent scent distribution.
- Skin and Hair Care: Commonly found in conditioners, creams, and gels, where it improves hydration and product feel.
4. Automotive and Industrial Applications
- Antifreeze and Coolant: MPG is used in cooling systems to prevent freezing and overheating, offering a less toxic alternative to ethylene glycol.
- Heat Transfer Fluid: It is utilized in HVAC systems, refrigeration, and solar energy applications due to its thermal stability and high boiling point.
- De-icing Applications: MPG lowers the freezing point of water, making it effective in de-icing solutions for vehicles and aircraft.
5. Paints, Coatings, and Inks
- Solvent in Coatings: MPG is used in water-based paints and coatings to improve flow, application, and uniform drying.
- Printing Inks: It helps maintain consistent viscosity and enhances print quality.
6. Tobacco and E-Liquid Industry
- E-Liquids: MPG serves as a carrier for nicotine and flavorings in e-cigarette liquids, producing vapor upon heating.
- Tobacco Processing: It acts as a humectant to retain moisture and prevent tobacco products from drying out.
7. Textile and Leather Industry
- Textile Finishing: MPG is used to improve softness and moisture retention in fabrics.
- Leather Processing: It helps condition leather, preventing cracking and drying during manufacturing.
8. Agricultural Industry
- Agrochemical Solvent: MPG acts as a solvent and carrier in pesticide and herbicide formulations, improving effectiveness.
- Animal Feed Additive: It is used as a humectant and preservative to maintain feed quality and moisture content.
9. Construction Industry
- Concrete Additives: MPG enhances workability, reduces cracking, and improves uniform distribution of additives in concrete.
- Sealants and Coatings: It is used in protective coatings and sealants due to its stability and moisture resistance.
10. Laboratory and Biotech Applications
- Chemical Processing: MPG is widely used as a solvent in laboratory and industrial chemical processes.
- Biological Preservation: It helps stabilize biological samples and maintain them in aqueous environments, especially in research applications.
Supply Locations
Propylene Glycol Food Grade supplier in Mumbai, Kandla, Kolkata, Chennai, Vizag. Food Grade Propylene Glycol manufacturer supplier in India.
Safety Data (MSDS)
| Porduct Name | Mono Propylene Glycol USP/IND |
| Part Number | RXSOL-95-1586-215 |
Company Details:
RX MARINE INTERNATIONAL
105, A wing , BSEL , TECH PARK.
VASHI ,NEW BOMBAY 400703 INDIA
Branch : Kandla, Mumbai , Chennai, Vizag, Kolkata, UAE , OMAN , CANADA and KENYA
| Phone | +91 22 20871200 - 1400 |
| Fax | +91 22 27612100 :::AOH :0091 9821214367 |
| mail@rxmarine.com | |
| Website | www.rxmraine.com |
| Product name | Cas No | EC No | Weight | Formula |
| Propylene glycol | 57-55-6 | 200-338-0 | 76,09 g/mol | C3H8O2 |
| Signal Word | No data available |
| Hazard Statements | No data available |
| Precautionary statements | No data available |
| Classification of the substance or mixture | No data available |
| Supplemental Hazard Statements | No data available |
| Other hazards | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| General advice | Show this material safety data sheet to the doctor in attendance |
| If inhaled | If breathed in, move person into fresh air. If not breathing, give artificial respiration. |
| Eye Contact | Flush eyes with water as a precaution. |
| Swallowed | Never give anything by mouth to an unconscious person. Rinse mouth with water. |
| Skin Contact | Wash off with soap and plenty of water. |
| Inhalation | No data available |
| Ingestion | No data available |
| Most important symptoms and effects, both acute and delaye | The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 |
| Indication of any immediate medical attention and special treatment needed | No data available |
| Flammability | No data available |
| Suitable extinguishing media | Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide |
| Unsuitable extinguishing media | For this substance/mixture no limitations of extinguishing agents are given |
| Special hazards arising from the substance or mixture | Carbon oxides |
| Further information | No data available |
|
Hazardous combustion products |
No data available |
| Advice for firefighters | Wear self-contained breathing apparatus for firefighting if necessary. |
| Protective Equipment | No data available |
| Specific Hazards Arising from the Chemical | No data available |
| Personal precautions, protective equipment and emergency procedures | Avoid breathing vapors, mist or gas. For personal protection see section 8. |
| Spillage | No data available |
| Personal Protection | No data available |
| Enviromental Precaution | No special environmental precautions required |
|
Methods and materials for containment and cleaning |
Keep in suitable, closed containers for disposal. |
| Reference to other sections | For disposal see section 13. |
| Advice on protection against fire and explosion | No data available |
| Incompatible materials | No data available |
| Hygiene measures | No data available |
| Advice on safe handling | For precautions see section 2.2. |
| Conditions for safe storage including any incompatibilities |
No data available |
| Storage conditions | Keep container tightly closed in a dry and well-ventilated place. Store in cool place. hygroscopic |
| Storage class | Storage class (TRGS 510) 10 Combustible liquids |
| Specific end use(s) | Apart from the uses mentioned in section 1.2 no other specific uses are stipulated |
| Advice on genera occupational hygiene | No data available |
| Exposure controls | Personal protective equipment |
| Engineering Control | No data available |
| Eye/face protection | Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Safety glasses |
| Body Protection | Impervious clothing, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. |
| Skin protection | Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Aldrich- W294004 Page 4 of 9 The life science business of Merck operates as MilliporeSigma in the US and Canada Break through time: 480 min Material tested:Dermatril® (KCL 740 / Aldrich Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, e-mail sales@kcl.de, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the EC approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use |
| Respiratory protection |
Respiratory protection not required. For nuisance exposures use type OV/AG (US) or type ABEK (EU EN 14387) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU)
|
| Other Protection Measure | No data available |
| Physical state | Liquid |
| Colour | Colorless |
| Odour | Weak characteristic odour |
| Odor Threshold | No data available |
| pH | No data available |
| Melting Point | -60 °C - lit |
| Boiling Point | 187 °C - lit |
| Flash Point | 103 °C - closed cup |
| Evaporation Rate | No data available |
| Flammability (solid, gas) | No data available |
| Explosive limits | No data Available |
| Upper/lower flammability or explosive limits | Upper explosion limit12,5 %(V) Lower explosion limit 2,6 %(V) |
| Autoignition temperature | No data available |
| Decomposition temperature | No data available |
| Vapour pressure | 0,11 hPa at 20 °C |
| Viscosity | No data available |
| Density | 1,036 g/cm3 at 25 °C - lit |
| Relative Density | No data available |
| Specific Gravity | No data available |
| Partition coefficient | Log Pow -0,8 at 25 °C |
| Explosive properties | No data available |
| Solubility | at 25 °C soluble |
| Ignition temperature | No data available |
| Particle characteristics | No data available |
| Reactivity | No data available |
| Chemical stability | The product is chemically stable under standard ambient conditions (room temperature) |
| Possibilityof hazardous reactions | No data available |
| Conditions to avoid | No data available |
| Incompatible materials |
Acid chlorides, Acid anhydrides, Oxidizing agents, Chloroformates, Reducing agentsAcid chlorides, Acid anhydrides, Oxidizing agents, Chloroformates, Reducing agents
|
| Hazardous decomposition products | In the event of fire: see section 5 |
| Acute toxicity | LD50 Oral - Rat - male and female - 22.000 mg/kg (ECHA) LD50 Dermal - Rabbit - > 2.000 mg/kg (ECHA) |
| Skin corrosion/irritation | Skin - Rabbit No skin irritation - 4 h (OECD Test Guideline 404) |
| Serious eye damage/irritation | Eyes - Rabbit No eye irritation (OECD Test Guideline 405) |
| Respiratory or skin sensitization | Maximization Test - Guinea pig negative (OECD Test Guideline 406) |
| Carcinogenicity | No data available |
| Germ cell mutagenicity | Test Type Chromosome aberration test in vitro Test system: Human lymphocytes Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 473 Result: negative Test Type: Ames test Test system: S. typhimurium Metabolic activation: with and without metabolic activation negative (ECHA) Test Type: Micronucleus test Species Mouse Cell type Bone marrow Application Route: Intraperitoneal Result negative (ECHA) Test Type Chromosome aberration test in vitro Species: Rat Cell type: Bone marrow Application Route: Oral Result: negative (ECHA) Test Type: dominant lethal test Species: Rat Application Route Oral Result: negative (ECHA) |
| Reproductive toxicity | No data available |
| Specific target organ toxicity - single exposure |
No data available
|
| Additional Information | Repeated dose toxicity - Rat - male - Oral - 2 yr - NOAEL (No observed adverse effect level) - 1.700 mg/kg Remarks: (ECHA) RTECS: TY2000000 To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Hazardous properties cannot be excluded but are unlikely when the product is handled appropriately. Handle in accordance with good industrial hygiene and safety practice. |
| Persistence and degradability | Biodegradability aerobic Dissolved organic carbon (DOC) - Exposure time 28 d Result: 98,3 % - Readily biodegradable. (OECD Test Guideline 301F) |
| Toxicity to fish | Static test LC50 - Oncorhynchus mykiss (rainbow trout) - 40.613 mg/l - 96 h (ECHA) |
| Toxicity to daphnia and other aquatic invertebrates | Static test LC50 - Ceriodaphnia dubia (water flea) - 18.340 mg/l - 48 h (US-EPA) |
| Toxicity | No data available |
| Toxicity to bacteria | NOEC - Pseudomonas putida - > 20.000 mg/l - 18 h (ECHA) |
| Toxicity to algae | Static test LC50 - Ceriodaphnia dubia (water flea) - 18.340 mg/l - 48 h (US-EPA) |
| Products Biodegradation | No data available |
| Mobility in soil | No data availalble |
| Results of PBT and vPvB assessment | This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher. |
| Endocrine disrupting properties | No data available |
| Other adverse effects | Biological effects: When discharged properly, no impairments in the function of adapted biological wastewater treatment plants are to be expected. Stability in water - 2,3 yr Remarks: reaction with hydroxyl radicals(IUCLID) |
| Product | Offer surplus and non-recyclable solutions to a licensed disposal company. |
| Contaminated packaging | Dispose of as unused product. |
| Waste treatment Method | No data available |
| UN number |
ADR/RID:- IMDG: - IATA:- |
| UN proper shipping name | ADR/RID:Not dangerous goods IMDG:Not dangerous goods IATA:Not dangerous goods |
| Transport hazard class(es) | ADR/RID:- IMDG:- IATA:- |
| Packaging group | ADR/RID:- IMDG: - IATA:- |
| Environmental hazards | ADR/RID:No IMDG Marine pollutant:No IATA:No |
| Special precautions for user | No data available |
| Further information | No data available |
| Safety, health and environmental regulations/legislation specific for the substance or mixture | This material safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006. |
| Other regulations | No data available |
| Chemical Safety Assessment | A Chemical Safety Assessment was not carried out for this substance. |
| Other Information |
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and weassume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rx Marine International has been advised of the possibility of such damages. DISCLAIMER OF LIABILITY :The information in this SDS was obtained from sources which we believe are reliable. However, the information is provided without any warranty, express or implied, regarding its correctness. The conditions or methods of handling, storage, use or disposal of the product are beyond our control and may be beyond our knowledge. For this and other reasons, we do not assume responsibility and expressly disclaim liability for loss, damage or expense arising out of or in any way connected with the handling, storage, use or disposal of the product. This MSDS was prepared and is to be used only for this product. If the product is used as a component in another product, this MSDS information may not be applicable. |
